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Anti-inflammatory strategy stops aggressive childhood cancer

Researchers at Karolinska Institutet and Karolinska University Hospital have discovered that an anti-inflammatory drug candidate inhibiting the prostaglandin E2 producing enzyme mPGES-1 in the tumour stroma reduces tumour growth in experimental neuroblastoma models. Read more: https://medicalxpress.com/news/2018-05-anti-inflammatory-strategy-aggressive-childhood-cancer.html

Childhood cancer survivors have higher risk of deadly heart disease in pregnancy

Girls who survive cancer have a higher risk of developing a deadly heart disease when pregnant later in life, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. Read more: https://www.escardio.org/The-ESC/Press-Office/Press-releases/childhood-cancer-survivors-have-higher-risk-of-deadly-heart-disease-in-pregnancy

Scientists reveal likely cause of childhood leukaemia

A major new analysis reveals for the first time the likely cause of most cases of childhood leukaemia, following more than a century of controversy about its origins. Read more: https://medicalxpress.com/news/2018-05-uk-scientist-reveals-childhood-leukaemia.html

How lessons from childhood cancer care could improve adult cancer care

Few life experiences are crueler than childhood cancer, but this blatant unfairness motivates some of the best, kindest and most heartfelt medical care. Clinicians in adult oncology can learn a lot from pediatric cancer practices. Read more: https://theconversation.com/how-lessons-from-childhood-cancer-care-could-improve-adult-cancer-care-94542

This 12-year-old leukemia survivor is fighting for equal access to medicine for all Canadians

In today’s golden age of cancer research, experimental therapies are curing tough-to-treat cancers like never before. But a child’s chances of receiving a potentially life-saving treatment may depend on whether he or she lives in the province where a clinical trial is taking place. Read more: https://www.theglobeandmail.com/canada/article-health-canada-urged-to-provide-funding-for-pediatric-cancer-costs/

Analysis emphasizes need for development of pediatric cancer-specific precision therapies

Researchers at St. Jude Children’s Research Hospital determined the genomic alterations that lead to cancer among children vary from those observed among adults. Read more: https://www.healio.com/hematology-oncology/pediatric-oncology/news/online/%7B7a279411-d13f-440e-a38c-c8bf47d2bca6%7D/analysis-emphasizes-need-for-development-of-pediatric-cancer-specific-precision-therapies

Chemotherapy-induced peripheral neuropathy persists for years in childhood cancer survivors

Chemotherapy-induced peripheral neuropathy commonly occurred in long-term childhood cancer survivors and persisted for years after treatment, according to findings published in JAMA Neurology. Read more: https://www.healio.com/hematology-oncology/pediatric-oncology/news/in-the-journals/%7Bc1f037ec-bd38-4389-b858-481fa8b29339%7D/chemotherapy-induced-peripheral-neuropathy-persists-for-years-in-childhood-cancer-survivors

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