Scientists from Northwestern Medicine have found that if they could stabilize the MLL protein -- the one responsible for the spread of the disease -- they could work to slow down the progression of leukemia in affected patients. Read more: https://www.consumeraffairs.com/news/promising-drug-for-pediatric-leukemia-in-developing-stages-122718.html
St. Jude Children's Research Hospital scientists have mapped the effects of aberrant biological machinery that drives a deadly brain cancer called diffuse intrinsic pontine glioma (DIPG). Read more: https://medicalxpress.com/news/2018-12-reveals-machinery-deadly-childhood-brain.html
New research refines existing evidence that survivors of childhood Hodgkin lymphoma face an elevated risk of developing various types of solid tumors many years later. Read more: https://medicalxpress.com/news/2018-12-survivors-childhood-hodgkin-lymphoma-high.html
A major breakthrough by researchers in Sydney has opened up the possibility for new and better treatments for ALL, the most common childhood cancer. Read more: https://www.dailytelegraph.com.au/news/nsw/childhood-leukaemia-medical-breakthrough-to-help-sufferers/news-story/c0442b7bc2cdb9ad5b8a028d668fb562
Researchers have identified markers of pediatric acute lymphoblastic leukaemia to predict early relapses by testing levels of nucleotide excision repair. Read more: https://www.europeanpharmaceuticalreview.com/news/82268/paediatric-all/
More than half of cancer survivors suffer from cognitive impairment from chemotherapy that lingers for months or years after the cancer is gone. In a new study explaining the cellular mechanisms behind this condition, scientists at the Stanford University School of Medicine have demonstrated that a widely used chemotherapy drug, methotrexate, causes a complex set of problems in three major cell types within the brain's white matter. Read more: https://medicalxpress.com/news/2018-12-chemo-brain-malfunction-cells.html
In collaboration with researchers from the Children's Cancer Institute (CCI) in Sydney, imaging was pivotal in understanding the mechanism of a promising new treatment developed at CCI for the childhood cancer neuroblastoma. Read more: https://medicalxpress.com/news/2018-12-imaging-protocol-molecular-mechanism-treatment.html