A study published by experts from the University of Seville and IBiS shows that the protein CD44 can contribute to the aggressive behavior of cancerous mother cells and the appearance of metastasis. Read more: https://eurekalert.org/pub_releases/2019-11/uos-asf112719.php

New research in mice indicates a possible targeted therapy for a form of pediatric cancer, acute lymphoblastic leukemia. Read more: https://www.futurity.org/acute-lymphoblastic-leukemia-pediatric-cancer-all-2220612-2/

"A study, led by experts at Newcastle University, UK, and published today in Clinical Cancer Research, has focussed on neuroblastoma cells which circulate in the blood and spread through the bone marrow. It is the first time that circulating neuroblastoma tumour cells have been identified in this way and experts say it is possible to test the effect of newer targeted types of treatments on the circulating tumour cells without the need for an invasive biopsy." Read more: https

Researchers have tested a new drug combination that shows promise for the treatment of several types of childhood brain cancers known as diffuse midline gliomas (DMG). Read more: https://www.biospace.com/article/new-hope-for-childhood-brain-cancers/

Parents and siblings of children with cancer can struggle with anxiety, stress and other mental health issues long after the initial cancer diagnosis, according to a new study that found elevated rates of mental health-related doctor’s visits among family members up to 20 years later. Read more: https://www.theglobeandmail.com/canada/article-pediatric-cancer-can-affect-mental-health-of-patients-families-long/

An international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be aimed at. Read more: https://www.sciencedaily.com/releases/2019/11/191112095750.htm

Children who have received radiotherapy for a brain tumour can develop cognitive problems later in life. In their studies on mice, researchers at Karolinska Institutet have now shown that the drug lithium can help to reverse the damage caused long after it has occurred. Read more: https://eurekalert.org/pub_releases/2019-11/ki-lcr111219.php#

A microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved survival in mice. Read more: https://www.eurekalert.org/pub_releases/2019-11/fda-nmr110719.php

About one in every 600 young adults in the U.S. — 270,000 people aged 20 to 39 — is a cancer survivor, based on federal data. For most, the transition from pediatric to adult care is full of gaps and pitfalls. Read more: https://www.inquirer.com/health/childhood-cancer-survivors-radiation-treatment-michael-schiller-20191105.html

An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia who relapse. Read more: https://www.eurekalert.org/pub_releases/2019-11/sjcr-css110119.php#