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Cranial radiotherapy associated with increased risk of anterior hypopituitarism

  • OPACC
  • Jan 13, 2015
  • 1 min read

In a retrospective review of over 700 childhood cancer survivors (CCS) treated with cranial radiotherapy, over 50% developed anterior pituitary dysfunction. A significant number of CCS who developed growth hormone and sex-hormone deficiencies were not recognized, leading to serious cardiovascular and musculoskeletal morbidities.

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