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Dexrazoxane Prevents Anthracycline-Related Cardiotoxicity in Childhood AML

New data from researchers at the Children’s Hospital of Philadelphia (CHOP) suggests use of dexrazoxane could provide some much-needed cardiovascular protection to pediatric patients undergoing chemotherapy for acute myeloid leukemia (AML). Read more: https://www.mdmag.com/medical-news/dexrazoxane-prevents-anthracyclinerelated-cardiotoxicity-in-childhood-aml

A promising new treatment for recurrent pediatric brain cancer

Two pediatric brain cancers that are challenging to treat if they recur, medulloblastoma and ependymoma, are the target of a clinical trial using a new type of therapy. Read more: https://www.eurekalert.org/pub_releases/2020-04/bcom-apn042720.php

New database of pediatric COVID-19 patients hopes to protect vulnerable children with cancer

St. Jude Children's Research Hospital has partnered with the International Society of Paediatric Oncology (SIOP) to open a new cloud-based database and resource center for doctors treating some of the most vulnerable COVID-19 patients: Children with cancer. Read more: https://www.techrepublic.com/article/new-database-of-pediatric-covid-19-patients-hopes-to-protect-vulnerable-children-with-cancer/

Potential childhood cancer treatment found in willow trees

A potential drug that can kill cancer cells has been discovered in willow trees, sparking hopes of new treatment for childhood cancers. Read more: https://www.sciencefocus.com/news/potential-childhood-cancer-treatment-found-in-willow-trees/

The moral and economic imperative of improving global cancer care for kids

"While the projections are sobering, there is a silver lining: Millions of these deaths can be averted with moderate investments aimed at expanding access to diagnostics, treatment, and supportive care." Read more: https://www.hsph.harvard.edu/news/features/the-moral-and-economic-imperative-of-improving-global-cancer-care-for-kids/

Brain Cancer in Infants Could Be Treated With Targeted Drugs

Brain cancer in infants is biologically distinct from other childhood brain tumors and could be successfully treated with targeted drugs, a new study has shown. Read more: https://www.technologynetworks.com/cancer-research/news/brain-cancer-in-infants-could-be-treated-with-targeted-drugs-332921

Inherited mutation can predispose children to a type of brain tumor

Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric medulloblastoma. Read more: https://www.eurekalert.org/pub_releases/2020-04/sjcr-imc033120.php#

Could a CAR-T Version 2.0 Be on the Way?

"A clinical trial will be the only way to truly answer whether this treatment will work in children with resistant disease, but the study shows clear evidence that it works pre-clinically." Read more: https://www.technologynetworks.com/tn/news/could-a-car-t-version-20-be-on-the-way-332799

Targeting a transporter to treat SHH medulloblastoma

Scientists at St. Jude Children's Research Hospital have identified a novel target for a type of pediatric brain tumor. Read more: https://www.eurekalert.org/pub_releases/2020-03/sjcr-tat033120.php

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