B-cell acute lymphoblastic leukaemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes (hyperdiploidy), a condition that leads to chromosomal instability. Now, a study published in  Cell Reports  reveals that this chromosomal instability caused by hyperdiploidy reduces the proliferation of the affected cells, delays their differentiation an

The field of pediatric oncofertility focuses on efforts to protect and preserve a patient’s fertility potential and reproductive hormone function from the effects of cancer treatments like chemotherapy and radiation — two considerations known to be extremely important for overall health and well-being. Read more: https://news.cuanschutz.edu/accords/beyond-survival-the-push-to-protect-future-fertility-for-pediatric-patients-with-cancer

Diagnosed with DIPG at age six, Lucas’ doctor Jacques Grill told Lucas’ parents, Cedric and Olesja, that he was unlikely to live very long. Instead of giving up hope, Cedric and Olesja flew Lucas to France to participate in a clinical trial called BIOMEDE, which tested new potential drugs against DIPG. Read more: https://www.upworthy.com/first-person-cured-of-dipg-ex1/

Hypofractionated palliative radiotherapy (PRT) effectively relieves pain in children with cancer, according to findings published in the EJC Pediatric Oncology . Researchers added that treatment was well-tolerated even after palliative reirradiation to the same anatomic site. Read more: https://www.cancertherapyadvisor.com/news/palliative-radiotherapy-symptom-relief-children/

The University of Queensland researchers used cutting-edge technology to map the biology of neuroblastoma—a cancer that typically develops in children under the age of 5—finding a hidden "shield" the tumors use as protection. Certain immune cells surrounding the tumor were also discovered to act as "bodyguards" for the cancer. Read more here: https://medicalxpress.com/news/2026-03-shields-bodyguards-scientists-uncover-hidden.html

Now, results obtained by a study led by the University of Trento in collaboration with Bambino Gesù Children's Hospital in Rome may pave a path to an organoid that could be used to study two common, aggressive childhood brain cancers. Read more: https://medicalxpress.com/news/2026-03-avatar-pediatric-brain-cancer-reality.html

Researchers have created experimental eye drops that use a molecule derived from pig semen that could treat a rare form of cancer, according to a recent study. Read more: https://www.fox13news.com/news/pig-semen-eye-drops-may-treat-rare-childhood-eye-cancer-study-says

Artificial intelligence (AI) could help physicians determine if survivors of childhood cancer need extra support — and the more information included in AI prompting, the better its performance. Read more: https://www.eurekalert.org/news-releases/1121751

Researchers in Japan find that B-cell acute lymphoblastic leukemia with NUTM1 gene rearrangements is a unique form of the disease, with a distinct pattern of gene activity and gene regulation that is highly sensitive to chemotherapy. Read more: https://www.asiaresearchnews.com/content/nutm1-rearrangements-cause-highly-treatable-form-infant-leukemia

An international team led by researchers at Baylor College of Medicine, Texas Children’s Hospital, McGill University and University of Pittsburgh School of Medicine has discovered what drives the growth of a lethal pediatric brain tumor called Posterior Fossa Type A (PFA) ependymoma. Read more: https://www.eurekalert.org/news-releases/1121004