Removing immune 'brake' improves CAR T-cell therapy for pediatric bone cancer
Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma. Read more: https://medicalxpress.com/news/2026-08-immune-car-cell-therapy-pediatric.html
4 days ago
Cardiometabolic Risk in Childhood Cancer Survivors Treated With Anthracyclines
Adult childhood cancer survivors treated with anthracyclines have elevated cardiometabolic risk, emphasizing the need for structured cardiac follow-up. Read more: https://www.oncologynurseadvisor.com/news/anthracyclines-cardiometabolic-risk-childhood-cancer-survivors-treatment/
6 days ago
Hodgkin Lymphoma Survivors Face Higher Long-Term Mortality
Adult survivors of Hodgkin lymphoma had nearly twice the mortality of the general United States population, according to a population-based retrospective cohort study of 20,057 long-term survivors. Read more: https://www.emjreviews.com/en-us/amj/hematology/news/hodgkin-lymphoma-survivors-face-higher-long-term-mortality/
7 days ago
Emotional health supports physical health in survivors of childhood cancer
Survivors of childhood cancer face many of the same emotional challenges as their peers, but they also carry worries that are unique to survivorship. Many know they are at a higher risk of developing chronic conditions earlier in life than other young people, and that awareness can become a lasting source of stress. Read more: https://www.stjude.org/research/progress/2026/emotional-health-supports-physical-health-in-survivors-of-childhood-cancer.html
Aug 31
Hidden aggressive cells reveal why some lower-risk childhood cancers turn deadly
New insights into why some children with rhabdomyosarcoma (RMS) develop aggressive disease despite being classified as non-high-risk have been uncovered. Read more: https://medicalxpress.com/news/2026-08-hidden-aggressive-cells-reveal-childhood.html
Aug 28
Personalized T-cell therapy eliminates detectable metastatic kidney tumor in adolescent after multiple relapses
Researchers and physicians at the Hopp Children's Cancer Center Heidelberg (KiTZ) and other leading cancer centers report an exceptional treatment outcome in an adolescent with an advanced, treatment-resistant kidney tumor. Read more: https://medicalxpress.com/news/2026-08-personalized-cell-therapy-metastatic-kidney.html
Aug 27
Protective drug dexrazoxane reduces heart damage in pediatric cancer survivors years after treatment ends
A new, high-quality study reveals that the cardioprotective drug dexrazoxane significantly reduces the heart damage caused by chemotherapy received by pediatric cancer patients 15 years or more after treatment ends. Read more: https://news.ufl.edu/2026/08/chemotherapy-heart-protecting-drug/
Aug 26
MBNL1 was identified as a potential cancer drug target for a type of childhood leukemia
Scientists found that the protein promotes survival of KMT2A-rearranged leukemia, presenting a previously unappreciated vulnerability. Read more: https://www.stjude.org/media-resources/news-releases/2026-medicine-science-news/mbnl1-identified-as-potential-cancer-drug-target-for-type-of-childhood-leukemia.html
Aug 25
What Limits Pediatric Oncology Trial Access for Marginalized Families?
In a study, Black and Hispanic parents were largely willing to enroll children in oncology trials, while clinicians cited hardship and gatekeeping as barriers. Read more: https://www.cancernetwork.com/view/what-limits-pediatric-oncology-trial-access-for-marginalized-families-
Aug 24
Biochemists discover new strategy to combat pediatric bone cancer
Researchers at the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center are zeroing in on less toxic and more targeted strategies to combat Ewing sarcoma, an aggressive and rare pediatric cancer that develops in the bones and soft tissues. Read more: https://medicalxpress.com/news/2026-08-biochemists-strategy-combat-pediatric-bone.html
Aug 21

