Researchers report encouraging early results from a first-in-human clinical trial led by Children's National Hospital using a new T-cell immunotherapy for children and young adults with some of the deadliest brain tumors, including diffuse intrinsic pontine glioma (DIPG) and relapsed central nervous system (CNS) tumors. Read more: https://medicalxpress.com/news/2026-06-tcell-therapy-tumor-proteins-early.html

Survivors of childhood cancer have a higher risk for antidepressant use and for combining these medications with other psychotropic drugs compared with individually-matched population references, according to findings published in EJC Paediatric Oncology. Read more: https://www.cancertherapyadvisor.com/news/childhood-cancer-survivors-antidepressants-other-psychotropics/

A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. The results, published in Molecular Therapy Oncology, present the first preclinical evidence showing the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer. Read more: https://medicalxpress.com/news/2026-06-anticancer-vaccine-early-success-neuroblastoma.html

Researchers at Wake Forest University School of Medicine found caregivers of children hospitalized for cancer and blood disorders may experience food insecurity during their child’s stay, even if they don’t face that issue at home, and it could be linked to longer stays. Read more: https://www.eurekalert.org/news-releases/1132410

Indiana University School of Medicine cancer researchers have identified a potential way to use existing, accessible drugs to combat juvenile myelomonocytic leukemia (JMML) by targeting a specific inflammatory pathway. Read more: https://firstwordpharma.com/story/7627533

In children and adolescents undergoing cancer treatment, exercise can be performed safely during and after therapy when appropriately supervised and individualized; further, appropriately prescribed exercise should be included as part of supportive cancer care, according to a new American College of Sports Medicine (ACSM) Expert Consensus Statement published by Fridh et al in the journal Medicine & Science in Sports & Exercise. Read more: https://ascopost.com/news/june-2026/n

A pediatric oncologist explains how scalp cooling, fertility preservation and early planning protect children with cancer well beyond treatment. Read more: https://www.curetoday.com/view/hair-loss-fertility-and-long-term-health-what-parents-of-kids-with-cancer-need-to-know

Through advanced genetic sequencing, chemotherapy and the expertise of a large medical team, doctors were able to identify a treatment approach tailored to Hadley's unique tumor. With the help of precision medicine and months of treatment, Hadley began defying expectations. Read more: https://www.cbsnews.com/colorado/news/childhood-brain-stem-cancer-survivor-colorado-girl/

This agent is more like a lock-and-key approach aimed at the biology driving the leukemia itself. The hope is not just survival, but a better life after survival, because for children, beating cancer isn't the end of the story. Read more: https://www.cbsnews.com/atlanta/news/emory-university-team-explores-promising-new-therapy-for-childhood-leukemia-with-fewer-toxic-effects/

A Children’s Hospital Los Angeles study has shed new light on the molecular drivers of FOXR2-activated CNS neuroblastoma, an extremely rare pediatric brain tumor that can be difficult to diagnose without advanced testing. Read more: https://www.newswise.com/articles/children-s-hospital-los-angeles-researchers-uncover-genetic-clues-to-rare-childhood-brain-tumor