A groundbreaking study led by researchers at Children’s Hospital Los Angeles offers critical insights into Ewing Sarcoma, a rare and aggressive bone and soft tissue cancer that primarily affects children and adolescents. Read more: https://www.morningstar.com/news/business-wire/20251013103275/childrens-hospital-los-angeles-researchers-discover-possible-cell-of-origin-for-ewing-sarcoma

Researchers at Cleveland Clinic Children’s have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults. Read more: https://newsroom.clevelandclinic.org/2025/10/09/new-research-reveals-genetic-link-to-most-common-pediatric-bone-cancer

The FDA has granted orphan drug designation (ODD) to AMXT 1501 in combination with difluoromethylornithine (Iwilfin; DFMO) for the treatment of patients with neuroblastoma. Read more: https://www.targetedonc.com/view/amxt-1501-and-dfmo-combination-achieve-fda-orphan-drug-designation

It is the leading cause of disease-related death in children, and while the five-year survival rate now stands at 85%, the diagnosis can send a wave of devastation, fear, anxiety and helplessness through not only the child, but also surrounding family, friends and community members. Read more: https://www.yourvalley.net/paradise-valley-independent/stories/we-cant-neglect-the-mental-toll-of-a-childhood-cancer-diagnosis,620036

Siblings’ emotional and developmental needs are affected across the course of a child’s cancer — not only at end of life. The research highlights the importance of screening for sibling distress and offering supports (peer support, counseling, family-centered communication, and validated sibling assessment tools). Read more: https://www.acco.org/for-siblings/

A new study by researchers at UC San Francisco and UC Davis has found that radiation from medical imaging may increase the risk of blood cancers in children. Read more: https://www.rttnews.com/amp/3575774/radiation-from-medical-scans-may-cause-thousands-of-childhood-cancers-study-says.aspx

Children’s Cancer Cause survey underscores the need for lifelong survivorship care, mental health support, and strong government investment in research. Read more: https://fox5sandiego.com/business/press-releases/ein-presswire/849874197/survey-childhood-cancer-survivors-seek-more-support-from-healthcare-providers-peers-and-policymakers/

Dr. Kim E. Nichols leans on findings from the Pediatric Cancer Genome Project to discover the role genes and ancestry play in the development of cancer. Read more: https://www.stjude.org/inspire/news/dr-kim-nichols-cancer-predisposition-clinic.html

Carboplatin plus etoposide, with or without focal treatments, may be safe and effective for patients with high-risk intraocular retinoblastoma, according to phase 2 results published in Cancer Medicine . Read more: https://www.cancertherapyadvisor.com/news/combo-safe-effective-high-risk-intraocular-retinoblastoma/

"Even though naxitamab appeared to have erased the cancer, Dr. Modak wanted to do everything possible to prevent the high-risk neuroblastoma from returning. He proposed that James receive a pioneering treatment: a cancer vaccine that would train his immune system to continuously be on guard to spot and fight malignant cells." Read more: https://www.mskcc.org/news/cancer-vaccine-could-prevent-neuroblastoma-from-returning-after-antibody-treatment