Sex and Age May Influence Comorbidities in Pediatric ALL
While the overall prevalence of comorbidities at diagnosis in pediatric patients with acute lymphoblastic leukemia (ALL) and...
Apr 15
Motor Deficits in Children Off Therapy for Acute Lymphoblastic Leukemia
Recent study results indicated that pediatric patients with acute lymphoblastic leukemia (ALL) were experiencing some motor skill impacts...
Apr 3
A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia
CAR-T cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many...
Mar 25
CAR-T Cell Therapy Shows EFS Benefit in Pediatric Leukemia Subset
Treatment with bicistronic CD19/CD22 CAR-T cell therapy has shown event-free survival improvements in children with relapsed or...
Dec 19, 2024
Global clinical trial shows improved survival rates for common childhood leukemia
Early study results were so promising that the trial closed early, with findings published in the New England Journal of Medicine ...
Dec 18, 2024
Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients...
Nov 27, 2024
A Tantalizing Childhood Cancer Discovery
A BC study found infant mice infected with a mild virus don’t develop leukemia. Could this work for humans? Read more:...
Nov 6, 2024
FDA Expands Approval for Jylamvo to Children With Acute Lymphoblastic Leukemia
The Food and Drug Administration (FDA) expanded the approval of Jylamvo (methotrexate) to include children with acute lymphoblastic...
Nov 5, 2024
Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia
A new study has uncovered molecular markers in blood at birth that are linked to later development of acute lymphoblastic leukemia (ALL),...
Oct 30, 2024
Pharmacotyping provides a precision medicine blueprint for acute lymphoblastic leukemia treatment
In a report published in Nature Medicine, St. Jude scientists examined how ALL cells respond to different therapeutics in the context of...
Jul 25, 2024