New discovery links circular DNA by-products to childhood leukaemia relapse
The new paper reveals for the first time that these DNA fragments can persist in cancer cells and may drive relapse in patients with...
Sep 30
Finding a clue to the origin of treatment-resistant leukemia in kids
Chemotherapy resistance is particularly common in what is known as T-ALL, a subtype of ALL. This recent study shows that the origin of...
Sep 26
Planned C-Sections Linked to Higher Risk of Cancer in Children
Planned caesarean births—"C-sections"—slightly raise the risk of some childhood cancers—particularly acute lymphoblastic leukemia (ALL),...
Sep 5
Timepoint at which developing B-cells become cancerous impacts leukemia treatment
Scientists at St. Jude Children’s Research Hospital and University Health Network showed that the stage of B-cell development at which...
Sep 4
Potential new treatment to tackle commonest form of childhood cancer
A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukaemia...
Jul 30
Duration of Overweight/Obesity During Treatment Linked to Worse Outcomes in Pediatric Leukemia Patients
New research on children diagnosed with acute lymphoblastic leukemia (ALL) shows that the longer a patient’s body mass index (BMI) falls...
Jul 24
Unmasking a hidden threat for optimal ALL treatment in children
Asparaginase (ASNase) remains a cornerstone of chemo regimens for ALL. But there’s a quiet threat that’s often missed: hypersensitivity...
Jun 24
Sex and Age May Influence Comorbidities in Pediatric ALL
While the overall prevalence of comorbidities at diagnosis in pediatric patients with acute lymphoblastic leukemia (ALL) and...
Apr 15
Motor Deficits in Children Off Therapy for Acute Lymphoblastic Leukemia
Recent study results indicated that pediatric patients with acute lymphoblastic leukemia (ALL) were experiencing some motor skill impacts...
Apr 3
A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia
CAR-T cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many...
Mar 25