Scientists from St. Jude Children’s Research Hospital have identified variants in two genes that may be associated with accelerated aging in childhood cancer survivors. Read more: https://ascopost.com/news/march-2022/study-identifies-genetic-variants-that-may-contribute-to-accelerated-aging-in-childhood-cancer-survivors/

Now cancer experts at the University of South Australia are striving to change these outcomes as new genetic research shows that up to 19 per cent of childhood AML cases are linked to rare genetic changes that may be inherited through family blood lines. Read more: https://www.newswise.com/articles/rare-genetic-anomaly-linked-to-20-of-childhood-acute-myeloid-leukemia-cases

For a paper published in Diabetes Care, Dr. Auger and colleagues examined the link between gestational diabetes and early versus late childhood cancer. Read more: https://www.physiciansweekly.com/the-link-between-gestational-diabetes-childhood-cancer

Survival following childhood cancer has increased considerably. In an observational cross-sectional study, we assessed the prevalence of dental developmental anomalies (DDA) among childhood cancer survivors according to types of anticancer treatment. Read more: https://www.nature.com/articles/s41598-022-08266-1

A researcher has found, through extensive data analysis, that the youngest patients with brain tumors -- those ages birth to 3 months -- have about half the five-year survival rate as children ages 1 to 19. Read more: https://www.sciencedaily.com/releases/2022/03/220318161427.htm

New research has begun to unravel the mystery of why a particular form of leukaemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children. Scientists have now found subtle differences in the cell type that causes B acute lymphoblastic leukaemia (B-ALL) that may help to explain why some cases are more severe than others. Read more: https://www.sciencedaily.com/releases/2022/03/220314120649.htm

Adding the proteasome inhibitor bortezomib to chemotherapy significantly improved overall survival in children and young adults with newly diagnosed T-cell lymphoblastic lymphoma (T-LL). Read more: https://www.newswise.com/articles/chop-led-study-finds-bortezomib-improves-survival-in-children-with-newly-diagnosed-t-cell-lymphoblastic-lymphoma

Amatruda spoke with Healio about the value of zebrafish models in understanding pediatric cancers, the major progress that has been made in treating these cancers, and the potential future implications of his research. Read more: https://www.healio.com/news/hematology-oncology/20220309/zebrafish-could-help-researchers-develop-treatments-for-childhood-cancers

Survivors of childhood cancer who become pregnant in adulthood are as likely to have healthy babies as those without a history of cancer, according to a new study published by Zgardau et al in the Journal of the National Cancer Institute. Read more: https://ascopost.com/news/march-2022/research-outlines-obstetric-and-perinatal-outcomes-for-female-survivors-of-childhood-cancer/

Written from the perspective of a bereaved sibling (OPACC family) in the hopes that it can help at least one person get through a difficult situation like this. Read more: https://medium.com/@janakalbasi/the-story-of-aryo-kalbasi-as-told-by-his-sister-f74c903f990b