CAR-T | opacc

Nov 14

Cell therapy fights lethal childhood brain cancer in Stanford Medicine trial

CAR-T cells show promise against pediatric diffuse midline gliomas, brain and spinal cord tumors that are among the deadliest cancers, a...

Oct 15

Children with aggressive blood cancer offered treatment cure hope

Youngsters with T-cell acute lymphoblastic leukaemia (T-ALL) will be offered CAR T-cell therapy targeted at a specific protein, which has...

Jun 3

CAR T cell therapy for pediatric brain cancer warrants further study

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s...

May 30

CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in phase I clinical trial

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s...

Mar 25

CAR T cell therapy for pediatric patients: What parents should know

CAR T cell therapy is a type of immunotherapy that modifies T cells, so they can detect and fight cancer cells. This therapy is...

Mar 7

Combining CAR-T cells and inhibitor drugs for high-risk neuroblastoma

Roberto Chiarle, MD, at Boston Children's Hospital and his colleagues now report a way to make CAR-T cell therapy work better in...

Feb 7

Beyond chemotherapy: Navigating the promise and perils of CAR-T therapy in pediatric cancer

Upon hearing the phrase ‘cancer treatment’, the first word that can typically spring to mind is chemotherapy – a primary therapy which...

Dec 21, 2023

Rethinking the Development of CAR T-Cell Products for Pediatric Cancer

In a commentary published in the Journal of Clinical Oncology, Claudia Rossig, MD, of the department of pediatric hematology and oncology...

Dec 7, 2023

Promising target for CAR T cells helps cancer trick the immune system

Scientists at St. Jude Children’s Research Hospital showed that GRP78 is a promising but complex target for CAR T–cell immunotherapy...

Nov 3, 2023

NIH researchers develop approach that could help supercharge T-cell therapies against solid tumors

Researchers at the National Institutes of Health have developed a way to potentially increase the effectiveness of T cell–based...

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The ticking ‘epigenetic’ clock measures true biological age

Serum protein panel test can help identify cardiomyopathy risk in childhood cancer survivors

UCalgary researchers help preserve future fertility options for children impacted by cancer

How a Penn State professor developed a cancer-fighting drug for kids

New insights into risk assessment of rare, aggressive tumors in children

CNIO opens up new research pathways against paediatric cancer Ewing sarcoma by discovering mechanisms that make it more aggressive

Larotrectinib Is Promising for Pediatric TRK Fusion-Positive CNS Tumors

Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia

If My Dying Daughter Could Face Her Mortality, Why Couldn’t the Rest of Us?

FDA Grants Rare Pediatric Designation to Elraglusib for Ewing Sarcoma