Mystery of treatment-resistant childhood leukemia uncovered
A new type of cancer cell that “warrants urgent investigation” has been discovered in childhood leukaemia and could impact clinical care. Research into new or repurposed treatments that target this new cell type could give hope to children and families worldwide. Read more: https://www.eurekalert.org/news-releases/1105676
Nov 26
Finding a clue to the origin of treatment-resistant leukemia in kids
Chemotherapy resistance is particularly common in what is known as T-ALL, a subtype of ALL. This recent study shows that the origin of...
Sep 26
New research from Children’s Hospital of Philadelphia and St. Jude poised to transform approach to diagnosing and treating acute leukemia in children
Researchers at Children’s Hospital of Philadelphia (CHOP), St. Jude Children’s Research Hospital (St. Jude) and the Children’s Oncology...
Aug 27, 2024
Refined Stratification and Frontline Targeted Therapies Explored in Pediatric T-ALL
The treatment of pediatric patients with T-cell acute lymphoblastic leukemia (T-ALL) has benefited from numerous advancements in...
Aug 11, 2023
New chemical technology leads to better targeted therapeutics against high-risk leukemia in the lab
Scientists from St. Jude Children’s Research Hospital have created an LCK targeted PROTAC, demonstrating its enhanced ability to kill...
Aug 26, 2022
First large-scale genomic analysis of key acute leukemia will likely yield new therapies
A consortium including St. Jude Children's Research Hospital and the Children's Oncology Group has performed an unprecedented genomic...
Jul 4, 2017