Survivors of childhood osteosarcoma and Ewing sarcoma (EWS) have an elevated risk of neurocognitive impairment, according to study findings published in the Journal of Cancer Survivorship. Read more: https://www.cancertherapyadvisor.com/home/cancer-topics/bone-cancer/bone-cancer-survivors-at-increased-risk-of-neurocognitive-difficulties/

Scientists have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients. Read more: https://www.sciencedaily.com/releases/2022/02/220217102047.htm

Researchers at University College London have discovered that disulfiram, an anti-alcoholism drug, may help to kill glioma cells in children. Read more: https://www.thebraintumourcharity.org/media-centre/news/research-news/alcohol-abuse-drug-may-hold-key-treating-aggressiv/

A Ludwig Cancer Research study has identified a potential vulnerability in neuroblastoma tumors that might be exploited to improve treatment of the aggressive childhood cancer, which accounts for roughly 15% of all deaths from pediatric malignancies. Read more: https://www.news-medical.net/news/20220207/Potential-tumor-vulnerability-may-be-exploited-to-improve-treatment-of-neuroblastoma.aspx

Today a group of Stanford scientists who have spent the past decade unlocking the glioma's secrets are publishing data in Nature from the trial Ward joined. He was one of the first four patients with diffuse intrinsic pontine glioma or a closely related cancer affecting the spinal cord to receive immune cells engineered to fight the disease. Read more: https://scopeblog.stanford.edu/2022/02/07/from-loss-comes-hope-pediatric-brain-tumor-treatment-shows-promise/

Scientists at St. Jude Children’s Research Hospital and the Cancer Research Center in Spain blocked development of acute lymphoblastic leukemia in mice with a genetic mutation that increases the risk of childhood cancer. Read more: https://www.stjude.org/media-resources/news-releases/2022-medicine-science-news/research-lays-foundation-for-prevention-of-most-common-childhood-cancer.html

Having a child diagnosed with cancer is a life-changing event. Childhood cancer not only impacts children undergoing treatment, it can also cause significant psychological distress for their parents or caregivers. Read more: https://www.newswise.com/articles/parents-of-children-with-cancer-may-need-psychological-support-as-well-as-their-child

Scientists at St. Jude Children’s Research Hospital have revealed how an inherited genetic variant turns on an oncogene, increasing the risk of developing childhood leukemia. Read more: https://www.stjude.org/media-resources/news-releases/2022-medicine-science-news/inherited-gene-variant-powers-up-an-oncogene-to-drive-a-high-risk-leukemia.html