AML | opacc

Jul 24

Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia

Pediatric acute myeloid leukemia (AML) accounts for 20% of all pediatric leukemia cases and is associated with poor outcomes, especially...

Jun 10

Researchers discover that a type of childhood leukemia originates during fetal development

A team of researchers has demonstrated that some childhood leukemias originate during embryonic development, although they do not...

Feb 8

‘We now know our enemy’: UBC study offers new hope for treating relapsed childhood leukemia

New therapies have dramatically improved survival rates among children with pediatric acute myeloid leukemia (pAML)—a cancer that starts...

Jan 24

Molecular ‘super-glue’ shows promise of cancer drug discovery platform

Today, St. Jude Children’s Research Hospital scientists published their work on SJ3149, a compound with broad activity against many...

Jan 18

Updated genomic landscape for pediatric acute myeloid leukemia enables new treatment possibilities

Scientists at St. Jude Children’s Research Hospital refined and enhanced the classification system for a type of pediatric leukemia using...

Dec 5, 2023

Scientists discover new Achilles heel of leukemia cells

A team led by Jan-Henning Klusmann from the Department of Pediatrics and Dirk Heckl from the Institute for Experimental Pediatric...

Sep 6, 2023

Homoharringtonine May be ‘Better Alternative’ to Etoposide In Pediatric AML

Use of homoharringtonine (HHT) may result in improved responses among patients with pediatric acute myeloid leukemia (AML) compared with...

Jun 19, 2023

New hope for children with rare, high-risk leukaemia thanks to world first research in Manchester

Pioneering research in Manchester has shown dramatic results for treating children with high-risk leukaemia (a type of blood cancer), who...

Mar 20, 2023

Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia

In some children, pediatric acute myeloid leukemia can become resistant to treatment; UC San Diego researchers think they now know why....

Jan 9, 2023

Two-year-old Millbrook boy’s cancer journey featured in charity’s 2023 calendar

As outlined in Ezra’s story, featured in Ontario Parents Advocating for Children with Cancer (OPACC)’s 2023 wall calendar, the Gulliver...

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The ticking ‘epigenetic’ clock measures true biological age

Serum protein panel test can help identify cardiomyopathy risk in childhood cancer survivors

UCalgary researchers help preserve future fertility options for children impacted by cancer

How a Penn State professor developed a cancer-fighting drug for kids

New insights into risk assessment of rare, aggressive tumors in children

CNIO opens up new research pathways against paediatric cancer Ewing sarcoma by discovering mechanisms that make it more aggressive

Larotrectinib Is Promising for Pediatric TRK Fusion-Positive CNS Tumors

Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia

If My Dying Daughter Could Face Her Mortality, Why Couldn’t the Rest of Us?

FDA Grants Rare Pediatric Designation to Elraglusib for Ewing Sarcoma