Protein activity reveals new childhood ALL combination treatment strategy
Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows....
Mar 2, 2022
Inherited gene variant powers up an oncogene to drive a high-risk leukemia
Scientists at St. Jude Children’s Research Hospital have revealed how an inherited genetic variant turns on an oncogene, increasing...
Feb 4, 2022
Genetic ancestry provides important context for understanding global diversity in childhood leukemia
St. Jude Children's Research Hospital scientists have shown that addressing racial disparities in acute lymphoblastic leukemia should...
Jan 28, 2022
Study Confirms Nutrient’s Role in Childhood Blood Cancer
A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute...
Dec 22, 2021
Long-Term Effects of Pediatric Acute Lymphoblastic Leukemia
Despite major advances in the treatment of acute lymphoblastic leukemia (ALL), adult survivors face long-term health consequences. A ...
Dec 14, 2021
USC study identifies new risk factor for most common childhood cancer, Acute Lymphoblastic Leukemia
According the research, children genetically predisposed to overproduce lymphocytes in relation to other white blood cells are at...
Sep 13, 2021
Pediatric ALL Relapse May Be Caused by Mutations From Chemotherapy
Chemotherapy is standard care for pediatric acute lymphoblastic leukemia (ALL), but new research shows thiopurines can cause mutations ...
Aug 11, 2021
International Collaboration Helps Refine Treatment for Childhood Leukemia
Scientists at St. Jude Children’s Research Hospital are working with colleagues in China to develop better therapy for childhood acute...
Jul 30, 2021
FDA Approves Rylaze as Alternative for Patients with ALL and Lymphoblastic Lymphoma
New FDA approval means that pediatric and adult patients with acute lymphoblastic leukemia (ALL) and lympoblastic lymphoma who are...
Jul 2, 2021
Clinical Challenges: Pediatric ALL in Children With Obesity
Although obesity has been strongly linked to 13 cancers in adults, and is suspected as a risk factor in many hematologic malignancies, ...
Jun 16, 2021