Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse
An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia...
Nov 5, 2019
Exercise capacity may affect cognitive health of survivors of childhood leukemia
A new study found a link between reduced exercise capacity and neurocognitive problems in survivors of acute lymphoblastic leukemia...
Oct 21, 2019
Childhood leukemia cannot hide from the immune system
"St. Jude Children's Research Hospital scientists have evidence that children with acute lymphoblastic leukemia mount a robust immune...
Jun 28, 2019
Goldilocks principle explains the origins of the most common children's cancer
Just as Goldilocks sought porridge that was "just right," St. Jude Children's Research Hospital scientists reported that targeting "just...
Jun 28, 2019
How conquering a rare leukemia in children revolutionized cancer care for millions
"That success story — one with deep Philadelphia roots — is even more phenomenal than it sounds. While ALL accounts for almost a third of...
Jun 11, 2019
Recovery twice as hard for survivors of childhood acute lymphoblastic leukemia
Nearly 90 percent of children with acute lymphoblastic leukemia (ALL) survive, yet the same treatments that save their life can adversely...
May 29, 2019
Research links development of childhood leukaemia to mistakes by the immune system
Genetic mutations that drive the development of a common type of childhood leukaemia can be traced back to errors by the immune system...
Mar 25, 2019
Researchers identify multiple new subtypes of most common childhood cancer
Researchers used integrated genomic analysis, including RNA sequencing, to define the genomic landscape of B-cell acute lymphoblastic...
Jan 17, 2019
Lead Researcher Highlights Tisagenlecleucel Benefit in Younger Leukemia Patients
The CD19-targeted CAR T-cell therapy, tisagenlecleucel (Kymriah) demonstrated durable remissions in pediatric and young adult patients...
Jan 3, 2019
FDA expands Sprycel approval to include certain children with acute lymphoblastic leukemia
The FDA expanded the approval of dasatinib tablets to include its use with chemotherapy for children aged 1 year or older with newly...
Jan 3, 2019