New research published in Nature finds that tumor cells within supratentorial ependymomas (SE)—an aggressive childhood brain cancer—cluster into distinct tumor cell populations. Read more: https://medicalxpress.com/news/2026-03-distinct-tumor-neighborhoods-treatments-aggressive.html

Researchers at The Institute of Cancer Research, London, led work to develop a large panel of patient-derived mouse models of paediatric-type diffuse high-grade glioma (PDHGG) – a group of brain tumours with poor survival rates. Using magnetic resonance imaging (MRI), the research team demonstrated that these models reproduce key biological and radiological features of the human disease. Read more: https://www.icr.ac.uk/about-us/icr-news/detail/advanced-imaging-reveals-how-ch

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Read more: https://www.technologynetworks.com/tn/news/three-childhood-cancers-have-a-shared-dependence-on-light-sensing-genes-410398

Researchers at St. Jude Children’s Research Hospital show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Read more: https://www.stjude.org/media-resources/news-releases/2026-medicine-science-news/cell-free-dna-offers-early-warning-for-bloodstream-infections-in-kids-with-leukemia.html

Survivors of childhood medulloblastoma who also had a history of posterior fossa syndrome experienced long-term neurocognitive and physical impairments, according to findings published in JAMA Network Open . Read more: https://www.cancertherapyadvisor.com/news/posterior-fossa-syndrome-neurocognitive-deficits-medulloblastoma-survivors/

Now, a new study is the first to assess the effect of pesticide exposures on the survival of children with leukemia. The study found a statistically significant link between residential rodenticide exposure and a higher risk in children of death from acute lymphoblastic leukemia (ALL), with about 10% of the exposed children dying within five years of diagnosis. Read more: https://beyondpesticides.org/dailynewsblog/2026/02/pesticide-exposure-again-linked-to-childhood-acute-lym

Research from St. Jude led by Heather Conklin, PhD, Department of Psychology & Biobehavioral Sciences, demonstrated that radiation therapy was a significant individual contributor to hearing loss, a risk directly linked to cognitive health, in children treated for ependymoma. Read more: https://www.eurekalert.org/news-releases/1117443

"By decentralizing these high-level services, the research team aimed to empower survivors with the knowledge necessary to pursue personalized survivorship care, which includes intensified screenings and prophylactic measures that can quite literally mean the difference between life and death." Read more: https://bioengineer.org/telehealth-is-transforming-genetic-care-for-childhood-cancer-survivors/

A randomized study found that early screening for risk factors was as helpful as screening plus one-on-one counseling. Read more: https://www.tctmd.com/news/adult-survivors-childhood-cancer-may-do-well-simple-strategy-cv-risk

Researchers have shown that subtle mutational differences in a gene called ATRX help explain why children with the same type of neuroblastoma respond differently to treatment. Read more: https://www.icr.ac.uk/about-us/icr-news/detail/new-research-reveals-how-subtle-genetic-differences-shape-neuroblastoma-behaviour