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Childhood leukemia cannot hide from the immune system

"St. Jude Children's Research Hospital scientists have evidence that children with acute lymphoblastic leukemia mount a robust immune response to their cancer. The findings, which appear today in the journal Science Translational Medicine, will likely aid development of immunotherapy for the most common childhood cancer." Read more:

Goldilocks principle explains the origins of the most common children's cancer

Just as Goldilocks sought porridge that was "just right," St. Jude Children's Research Hospital scientists reported that targeting "just right" levels of a mutant protein may offer a novel therapeutic approach to some cases of childhood leukemia. Read more:

Survivors of childhood brain tumors experience lasting cognitive and socioeconomic burdens

Survivors of childhood brain tumors who received radiotherapy and were very young at the time of diagnosis may experience cognitive and socioeconomic burdens decades after treatment, according to a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. Read more:

How do birth defects affect childhood cancer risk?

Children with birth defects may be at increased risk for childhood cancer, a new study finds. Read more:

Breast Cancer Screening Can Begin Later in Childhood Cancer Survivors

In female survivors of childhood cancers with a history of chest irradiation, initiation of breast cancer screening at age 30 years may be preferable to the current practice of initiating screening at age 25 years due to cost and quality-of-life factors, according to a new modeling analysis. Read more:

Cancer Survivors Deserve Coordinated Care

"We live in the age of tech-savviness where I can hail a ride or order food at the touch of a button. But when I move across the country and transfer my medical care to a new provider, I’m expected to bring paper copies of all of my medical records and succinctly describe my detailed and complex medical history in 30 seconds." Read more:

How conquering a rare leukemia in children revolutionized cancer care for millions

"That success story — one with deep Philadelphia roots — is even more phenomenal than it sounds. While ALL accounts for almost a third of pediatric cancers, it is a rare cancer overall, with about 2,900 annual diagnoses in the United States. Yet this uncommon malignancy is the tie that binds giants of oncology research, scientific breakthroughs, revolutionary drugs, and startling philanthropy, not to mention a Pulitzer Prize-winning book that became an acclaimed PBS documentary series." Read more:

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