Genetic insights reveal pathways of childhood kidney cancer development
Researchers at the Wellcome Sanger Institute, Cambridge University Hospitals NHS Foundation Trust, Great Ormond Street Hospital, the...
Jan 24
CKD, Albuminuria Risk Factors Identified in Childhood Cancer Survivors
Childhood cancer survivors treated with nephrectomy and potentially nephrotoxic therapy are at increased risk for chronic kidney disease...
Oct 25, 2022
Study finds that one third of children with a kidney tumor have hereditary predisposition
In a new study, researchers at the Princess Máxima Center for pediatric oncology in Utrecht, the Netherlands, mapped out hereditary...
Mar 4, 2022
Cellular signatures of kidney tumours discovered
The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger...
Jun 24, 2021
Researchers discover a new mechanism in childhood kidney cancer
"To execute their respective manuals, the cells employ so-called chromatin reader proteins that identify which gene is up for expression....
Dec 20, 2019
Root of childhood kidney cancer discovered
"A fundamental change in our understanding of the childhood kidney cancer Wilms' tumour is on the horizon, after the discovery of its...
Dec 6, 2019
Trial to assess novel targeted therapy for rare form of kidney cancer
A preclinical study that yielded new insights into a rare pediatric malignancy laid the foundation for a phase 2 trial that is evaluating...
Apr 16, 2019
Kidney cancer's developmental source revealed
In the first experiment of its kind, scientists have revealed the precise identity of cancer cells of the most common childhood and adult...
Aug 13, 2018
New genetic cause of kidney cancer in children discovered
Scientists have identified a new genetic cause of a childhood kidney cancer called Wilms tumour – revealing insights into how loss of...
May 29, 2017
Researchers discover genetic cause of second-most common kidney cancer in children
The genetic basis of clear cell sarcoma of the kidney (CCSK), a high-risk childhood cancer known for metastasizing to bone and brain, has...
Nov 19, 2015