Forty years of studies find higher cancer risks among children exposed during pregnancy and early life to pesticides used on farms, lawns, gardens, and pets. Read more: https://usrtk.org/healthwire/pesticide-use-linked-to-childhood-leukemia-brain-tumors/

John Bushweller, PhD, Professor of Molecular Physiology and Biological Physics at UVA and co-leader of the Cancer Biology Program at UVA Comprehensive Cancer Center, is collaborating with C-Further, an international consortium dedicated to advancing new therapies for childhood cancers, to develop a new treatment option that targets a transcription factor that fuels Ewing Sarcoma. The goal is a new drug that could offer better outcomes with less toxicity. Read more: https://ww

Following induction treatment for high-risk neuroblastoma, more than half of children experience cisplatin-induced hearing loss (CIHL), according to research published in JCO Clinical Advances. Read more: https://www.cancertherapyadvisor.com/news/cisplatin-hearing-loss-pediatric-high-risk-neuroblastoma/

Nagourney Cancer Institute and Metabolomycs with the FibroFighters Foundation showed fibrolamellar cancers appear to arise through changes in cellular metabolism. Read more: https://finance.yahoo.com/sectors/healthcare/articles/breakthrough-highly-lethal-childhood-cancer-140000323.html

"The biology has been pointing in this direction for a decade. The regulatory architecture is in place. The incentives exist. What happens in the next generation of molecularly targeted oncology programs will depend on whether protocol teams treat that nine-year-old’s NTRK fusion as a scheduling problem for post-approval — or as the enrollment criterion she was always supposed to be." Read more: https://www.clinicaltrialvanguard.com/opinion/pediatric-oncology-keeps-getting-tr

Healthy lifestyles can reduce the risk of cardiovascular disease and other complications in childhood cancer survivors. These are the findings of two new international studies. Read more: https://www.eurekalert.org/news-releases/1130093