Childhood acute leukemia survivors with Down syndrome at higher risk for late mortality
Childhood acute leukemia survivors with Down syndrome had increased risk for late mortality not attributable to cardiac- or subsequent ...
Mar 8, 2022
Protein activity reveals new childhood ALL combination treatment strategy
Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows....
Mar 2, 2022
Research lays a foundation for prevention of the most common childhood cancer
Scientists at St. Jude Children’s Research Hospital and the Cancer Research Center in Spain blocked development of acute lymphoblastic...
Feb 8, 2022
Mortality Risk Later in Life May Be Increased in Childhood Leukemia Survivors With Down Syndrome
Patients with Down syndrome have an increased risk for leukemia during childhood, and toxicities related to treatment may be more common...
Jan 5, 2022
Study Confirms Nutrient’s Role in Childhood Blood Cancer
A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute...
Dec 22, 2021
Long-Term Effects of Pediatric Acute Lymphoblastic Leukemia
Despite major advances in the treatment of acute lymphoblastic leukemia (ALL), adult survivors face long-term health consequences. A ...
Dec 14, 2021
‘Sleeping’ cancer cells explain why childhood leukaemia returns after years of treatment
Leukaemic cancer cells can ‘go to sleep’ and thus avoid the effects of chemotherapy, sometimes for years. It turns out that whether the...
Dec 1, 2021
Risk of Leukemia in Children with Down Syndrome
Leukemia is the most common childhood cancer. Although advances in treatment have led to high cure rates of childhood leukemia,...
Oct 7, 2021
Study illuminates genetic understanding of aggressive childhood leukemias
New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when...
Aug 23, 2021
Can leukemia in children with Down syndrome be prevented?
For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down...
Jul 12, 2021