Potential new treatment to tackle commonest form of childhood cancer
A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukaemia...
Jul 30
Duration of Overweight/Obesity During Treatment Linked to Worse Outcomes in Pediatric Leukemia Patients
New research on children diagnosed with acute lymphoblastic leukemia (ALL) shows that the longer a patient’s body mass index (BMI) falls...
Jul 24
LLS Expands its Global Master Trial for Hard-To-Treat Leukemias in Children
The Leukemia & Lymphoma Society (LLS) announced today the first pediatric patient has received treatment in a new subtrial of its...
Jun 27
Unmasking a hidden threat for optimal ALL treatment in children
Asparaginase (ASNase) remains a cornerstone of chemo regimens for ALL. But there’s a quiet threat that’s often missed: hypersensitivity...
Jun 24
Sex and Age May Influence Comorbidities in Pediatric ALL
While the overall prevalence of comorbidities at diagnosis in pediatric patients with acute lymphoblastic leukemia (ALL) and...
Apr 15
Motor Deficits in Children Off Therapy for Acute Lymphoblastic Leukemia
Recent study results indicated that pediatric patients with acute lymphoblastic leukemia (ALL) were experiencing some motor skill impacts...
Apr 3
A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia
CAR-T cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many...
Mar 25
Menin inhibitor clinical trial puts pediatric leukemia patient in remission
“Patient response to revumenib has been good in other clinical trials,” explains Cuglievan. “But it’s also been short-lived when used...
Dec 27, 2024
CAR-T Cell Therapy Shows EFS Benefit in Pediatric Leukemia Subset
Treatment with bicistronic CD19/CD22 CAR-T cell therapy has shown event-free survival improvements in children with relapsed or...
Dec 19, 2024
Global clinical trial shows improved survival rates for common childhood leukemia
Early study results were so promising that the trial closed early, with findings published in the New England Journal of Medicine ...
Dec 18, 2024