Targeting fusion protein’s role in childhood leukemia produces striking results
Investigators have discovered how NUP98-fusion proteins drive pediatric acute myeloid leukemia, identifying novel single-agent and...
Aug 29, 2025
Potential new treatment to tackle commonest form of childhood cancer
A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukaemia...
Jul 30, 2025
Duration of Overweight/Obesity During Treatment Linked to Worse Outcomes in Pediatric Leukemia Patients
New research on children diagnosed with acute lymphoblastic leukemia (ALL) shows that the longer a patient’s body mass index (BMI) falls...
Jul 24, 2025
LLS Expands its Global Master Trial for Hard-To-Treat Leukemias in Children
The Leukemia & Lymphoma Society (LLS) announced today the first pediatric patient has received treatment in a new subtrial of its...
Jun 27, 2025
Unmasking a hidden threat for optimal ALL treatment in children
Asparaginase (ASNase) remains a cornerstone of chemo regimens for ALL. But there’s a quiet threat that’s often missed: hypersensitivity...
Jun 24, 2025
Sex and Age May Influence Comorbidities in Pediatric ALL
While the overall prevalence of comorbidities at diagnosis in pediatric patients with acute lymphoblastic leukemia (ALL) and...
Apr 15, 2025
Motor Deficits in Children Off Therapy for Acute Lymphoblastic Leukemia
Recent study results indicated that pediatric patients with acute lymphoblastic leukemia (ALL) were experiencing some motor skill impacts...
Apr 3, 2025
A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia
CAR-T cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many...
Mar 25, 2025
Menin inhibitor clinical trial puts pediatric leukemia patient in remission
“Patient response to revumenib has been good in other clinical trials,” explains Cuglievan. “But it’s also been short-lived when used...
Dec 27, 2024
CAR-T Cell Therapy Shows EFS Benefit in Pediatric Leukemia Subset
Treatment with bicistronic CD19/CD22 CAR-T cell therapy has shown event-free survival improvements in children with relapsed or...
Dec 19, 2024

