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Cancer Sequencing Initiative Discovers Mutations Tied to Aggressive Childhood Brain Tumors

MEMPHIS, Tenn., Jan. 29, 2012 /PRNewswire via COMTEX/ -- St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project provides first evidence linking cancer to mutations in genes involved in DNA organization

Researchers studying a rare, lethal childhood tumor of the brainstem discovered that nearly 80 percent of the tumors have mutations in genes not previously tied to cancer. Early evidence suggests the alterations play a unique role in other aggressive pediatric brain tumors as well.

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