Biological pathways found that drive genomic changes and bone metastasis in Ewing Sarcoma
- OPACC
- May 3, 2022
- 1 min read
In studies using mice grafted with human Ewing sarcoma tissue, researchers from Georgetown University Medical Center and colleagues have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, thereby allowing cancer cells to make genetic changes so they can metastasize to the bone and thrive even when exposed to chemotherapy.
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