Change in MYCN-driven cell state opens therapeutic window in high-risk neuroblastoma

A switch between cell states within MYCN-amplified neuroblastoma promotes KDM4, inhibition of which shows promising anticancer potential.

Unexpected role of OTX2 drives aggressive medulloblastoma

Pharmacotyping provides a precision medicine blueprint for acute lymphoblastic leukemia treatment

Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia

Proton therapy improves neurocognitive outcomes of childhood craniopharyngioma

Assembling a molecular mosaic for pediatric brain tumors

This kids’ brain cancer is incurable — but immune therapy holds promise

Research takes on the long-term health of childhood cancer survivors

Stem-like cells found to drive growth of aggressive pediatric brain tumors

Risk for death significantly higher among underweight childhood cancer survivors

Racial differences seen in epigenetic age acceleration in childhood cancer survivors