Children’s Hospital of Philadelphia Researchers Find that Missing Messenger RNA Fragments Could be Key to New Immunotherapy for Hard-to-Treat Tumors
A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing...
Oct 8
New research shows promise for targeted therapies for pediatric gliomas
A collaborative study between Dana-Farber Cancer Institute and the Broad Institute found that 8.9% of children with glioma, the most...
Sep 24
Molecular testing unveils new insights into adolescent and young adult brain cancer
Part of a broader research study, the findings are helping to shape potential treatment approaches for patients with glioma based on the...
Aug 27
FDA Grants Rare Pediatric Designation to Treatment With NEO100 in Brain Cancer
The FDA has granted Rare Pediatric Disease Designation for NEO100 in the treatment of pediatric-type diffuse high-grade gliomas, a type...
Apr 10
Trial Shows Targeted Treatment for Childhood Brain Tumor is Safe
A Phase I clinical trial demonstrated that a targeted approach to treating a deadly brain tumor in children called diffuse intrinsic...
Apr 7
Experimental treatment borrowed from blood cancer shows promise for pediatric brain tumors
In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts caution that...
Mar 24
New therapeutic approach shows promise for pediatric high-grade gliomas
Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months...
Mar 18
Cell therapy fights lethal childhood brain cancer in Stanford Medicine trial
CAR-T cells show promise against pediatric diffuse midline gliomas, brain and spinal cord tumors that are among the deadliest cancers, a...
Nov 14, 2024
Targeted therapy and radiation synergize in pediatric high-grade glioma
Research at St. Jude recently showed that the drug capmatinib is effective at crossing the blood-brain-barrier, synergizing with...
Nov 8, 2024
First-of-their-kind findings turn conventional wisdom about diffuse hemispheric glioma on its head
Diffuse hemispheric glioma, H3G34-mutant (DHG-H3G34) is a type of high-grade glioma that typically affects adolescents and young adults....
Oct 24, 2024