First child cured of rare brain tumor 'offers real hope'
The Belgian boy is the first child in the world to have been cured of brainstem glioma, a particularly brutal cancer, according to the...
Feb 22, 2024
Dabrafenib and trametinib – a new treatment on the horizon?
Recent research suggests that there could be a new treatment on the horizon for some children diagnosed with low and high-grade gliomas....
Dec 18, 2023
Tafinlar Plus Mekinist Shows Benefits In Pediatric Glioma
A recent phase 2 trial revealed that the combination of Tafinlar and Mekinist benefitted children with BRAF-mutated low-grade gliomas....
Dec 12, 2023
Promising investigational therapy improves survival in aggressive childhood brain tumor
An international team of investigators has identified a drug candidate that nearly doubles survival rates for patients with diffuse ...
Dec 4, 2023
FDA Gives Priority Review to Tovorafenib in Pediatric Low-Grade Glioma
The FDA has granted priority review to a new drug application (NDA) for single-agent tovorafenib (DAY101) as a treatment for those with...
Nov 6, 2023
Lenalidomide Demonstrates Promising Activity in Pediatric Gliomas/Astrocytomas
The immunomodulatory agent lenalidomide (Revlimid) appeared clinically active and tolerable in pilocytic astrocytomas and optic pathway...
Jul 6, 2023
Developing novel treatments for childhood solid cancers
With a particular focus on glioma, Dr Peter J Houghton from Greehey Children’s Cancer Research Institute outlines the barriers that have...
Jul 4, 2023
New Drug Shows ‘Encouraging’ Outcomes for Pediatric Brain Tumor Treatment
Treatment with tovorafenib led to a 64% overall response rate in patients with recurrent or progressive pediatric low-grade glioma, study...
Jan 12, 2023
Dabrafenib + Trametinib Improve Overall Response Rates in Pediatric Patients with Low-Grade Gliomas
The combination of two targeted therapies, the BRAF inhibitor dabrafenib and the MEK inhibitor trametinib, significantly increased the...
Jun 9, 2022
Study finds jumping 'junk' DNA is a novel cause of childhood brain cancer
Scientists have found a novel cause of aggressive pediatric brain cancer. The St. Jude Children's Research Hospital study is the first to...
Apr 26, 2022