gliomas | opacc 3/4

Jun 9, 2022

Dabrafenib + Trametinib Improve Overall Response Rates in Pediatric Patients with Low-Grade Gliomas

The combination of two targeted therapies, the BRAF inhibitor dabrafenib and the MEK inhibitor trametinib, significantly increased the...

Apr 26, 2022

Study finds jumping 'junk' DNA is a novel cause of childhood brain cancer

Scientists have found a novel cause of aggressive pediatric brain cancer. The St. Jude Children's Research Hospital study is the first to...

Feb 11, 2022

Alcohol abuse drug may hold key to treating aggressive childhood brain tumours

Researchers at University College London have discovered that disulfiram, an anti-alcoholism drug, may help to kill glioma cells in...

Jul 26, 2021

Geneticists Reveal How Mutation Causes a Devastating Childhood Cancer

Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable ...

Aug 25, 2020

Blocking copper uptake in tumor cells may be clue to boosting immune system

Researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to...

Apr 3, 2020

Brain Cancer in Infants Could Be Treated With Targeted Drugs

Brain cancer in infants is biologically distinct from other childhood brain tumors and could be successfully treated with targeted drugs,...

Nov 25, 2019

Two-Drug Combo Shows Promise in Treating Childhood Brain Cancers

Researchers have tested a new drug combination that shows promise for the treatment of several types of childhood brain cancers known as...

Apr 27, 2018

Single-cell study in a childhood brain tumor affirms the importance of context

In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential...

Nov 16, 2017

Brain cancer treatment previously featured on 60 Minutes now available to children

A Phase 1 clinical trial leveraging the re-engineered polio virus is now open for enrollment to children 12 years and older at the...

Nov 14, 2017

Liquid biopsy spots aggressive pediatric brainstem cancer earlier without surgery

A particularly aggressive form of pediatric cancer can be spotted reliably by the genetic fragments it leaves behind in children's...

3

CNIO opens up new research pathways against paediatric cancer Ewing sarcoma by discovering mechanisms that make it more aggressive

Larotrectinib Is Promising for Pediatric TRK Fusion-Positive CNS Tumors

Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia

If My Dying Daughter Could Face Her Mortality, Why Couldn’t the Rest of Us?

FDA Grants Rare Pediatric Designation to Elraglusib for Ewing Sarcoma

Self-reported screening can reduce distressing symptoms for pediatric patients with cancer

Cell therapy fights lethal childhood brain cancer in Stanford Medicine trial

Increased Surveillance Recommended for Children at Risk for Hematopoietic Malignancy Predisposition

Targeted therapy and radiation synergize in pediatric high-grade glioma

Even 15 Years Later, Childhood Cancer Survivors More Likely to Develop Leukemia