May 14
‘Kinder’ treatment for childhood brain cancer to be offered by NHS in England
Dabrafenib with trametinib can halt growth of some tumours for more than three times as long as standard chemotherapy, study shows. Read...
Mar 8
Study: Improved Chemotherapy and Surgery Eliminating Need for Radiation for Low-Grade Gliomas
Successful outcomes from evolving surgical and chemotherapy treatments for pediatric low-grade glioma (pLGG) have greatly reduced the...
Feb 22
First child cured of rare brain tumor 'offers real hope'
The Belgian boy is the first child in the world to have been cured of brainstem glioma, a particularly brutal cancer, according to the...
Dec 18, 2023
Dabrafenib and trametinib – a new treatment on the horizon?
Recent research suggests that there could be a new treatment on the horizon for some children diagnosed with low and high-grade gliomas....
Dec 12, 2023
Tafinlar Plus Mekinist Shows Benefits In Pediatric Glioma
A recent phase 2 trial revealed that the combination of Tafinlar and Mekinist benefitted children with BRAF-mutated low-grade gliomas....
Dec 4, 2023
Promising investigational therapy improves survival in aggressive childhood brain tumor
An international team of investigators has identified a drug candidate that nearly doubles survival rates for patients with diffuse ...
Nov 6, 2023
FDA Gives Priority Review to Tovorafenib in Pediatric Low-Grade Glioma
The FDA has granted priority review to a new drug application (NDA) for single-agent tovorafenib (DAY101) as a treatment for those with...
Jul 6, 2023
Lenalidomide Demonstrates Promising Activity in Pediatric Gliomas/Astrocytomas
The immunomodulatory agent lenalidomide (Revlimid) appeared clinically active and tolerable in pilocytic astrocytomas and optic pathway...
Jul 4, 2023
Developing novel treatments for childhood solid cancers
With a particular focus on glioma, Dr Peter J Houghton from Greehey Children’s Cancer Research Institute outlines the barriers that have...
Jan 12, 2023
New Drug Shows ‘Encouraging’ Outcomes for Pediatric Brain Tumor Treatment
Treatment with tovorafenib led to a 64% overall response rate in patients with recurrent or progressive pediatric low-grade glioma, study...