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Unmasking a hidden threat for optimal ALL treatment in children

Jun 24, 2025
1 min read

Asparaginase (ASNase) remains a cornerstone of chemo regimens for ALL. But there’s a quiet threat that’s often missed: hypersensitivity reactions to E. coli ASNase, particularly its pegylated form, PEG-ASNase. These allergic reactions may be a common reason patients stop or don’t get optimal dosing.


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