drugs | opacc

FDA Grants Orphan Drug Designation to Opaganib in Neuroblastoma

The FDA has granted a second orphan drug designation to opaganib in oncology, this time for patients with neuroblastoma. Read more:...

FDA Approves Retevmo for RET-Positive Pediatric Cancers

The Food and Drug Administration (FDA) granted an accelerated approval to Retevmo (selpercatinib) for the children aged two and older...

Development of novel therapies for pediatric cancer: Successes and challenges

Peter J. Houghton from Greehey Children’s Cancer Research Institute and Mary-Ann Bjornsti from the University of Alabama discuss some of...

Epigenetic Combination Therapy Could Overcome Treatment Resistance in Epithelioid Sarcomas and Rhabdoid Tumors

Epithelioid sarcoma, a rare aggressive cancer that usually strikes young adults, and rhabdoid tumors, which affect children, have long...

Experimental Drug May Slow Childhood Brain Tumors

The drug tovorafenib may halt the growth of or shrink some childhood brain tumors, according to a clinical trial published in Nature...

How research helped lead to FDA approval of a pediatric neuroblastoma drug

The drug, called eflornithine (DFMO) and newly branded as IWILFIN by US WorldMeds, reduces the risk of relapse for pediatric high-risk...

A well-meaning FDA policy is a threat to pediatric cancer treatment

The medical community today faces a deceptively simple question: How quickly should we act when a child’s life is on the line? I’m a...

FDA Gives Priority Review to Tovorafenib in Pediatric Low-Grade Glioma

The FDA has granted priority review to a new drug application (NDA) for single-agent tovorafenib (DAY101) as a treatment for those with...

FDA Expands Rozlytrek Indication to Include Some Solid Tumors in Children at Least 1 Month Old

The Food and Drug Administration (FDA) approved an expanded indication for Rozlytrek (entrectinib) to include children older than one...

Second Dose of Palonosetron Reduces CINV in Pediatric Cancer Patients

An additional dose of palonosetron can help prevent chemotherapy-induced nausea and vomiting (CINV) in children with cancer who are...

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FDA Grants Orphan Drug Designation to Opaganib in Neuroblastoma

After my daughter's cancer, I wanted to control her entire life. Then she went to college.

When Childhood Cancer Survivors Face Sexual Challenges

Early interventions may improve long-term academic achievement in young childhood brain tumor survivors

Immunotherapy for children with primary liver carcinomas: Research offers new hope

Pediatric psychologist explains how to support your child's development after a cancer diagnosis

Adult Survivors of Childhood Cancer Have High Prevalence of Chronic Pain

Spontaneous Remission in Childhood Cancer Rare but Fleeting

First successful treatment of pediatric high-risk refractory neuroblastoma with PARP inhibition

Researchers identify malignant cells responsible for relapse in high-risk neuroblastoma