Epigenetic Combination Therapy Could Overcome Treatment Resistance in Epithelioid Sarcomas and Rhabdoid Tumors
Epithelioid sarcoma, a rare aggressive cancer that usually strikes young adults, and rhabdoid tumors, which affect children, have long...
Feb 16, 2024
Experimental Drug May Slow Childhood Brain Tumors
The drug tovorafenib may halt the growth of or shrink some childhood brain tumors, according to a clinical trial published in Nature...
Jan 31, 2024
How research helped lead to FDA approval of a pediatric neuroblastoma drug
The drug, called eflornithine (DFMO) and newly branded as IWILFIN by US WorldMeds, reduces the risk of relapse for pediatric high-risk...
Dec 20, 2023
A well-meaning FDA policy is a threat to pediatric cancer treatment
The medical community today faces a deceptively simple question: How quickly should we act when a child’s life is on the line? I’m a...
Dec 16, 2023
FDA Gives Priority Review to Tovorafenib in Pediatric Low-Grade Glioma
The FDA has granted priority review to a new drug application (NDA) for single-agent tovorafenib (DAY101) as a treatment for those with...
Nov 6, 2023
FDA Expands Rozlytrek Indication to Include Some Solid Tumors in Children at Least 1 Month Old
The Food and Drug Administration (FDA) approved an expanded indication for Rozlytrek (entrectinib) to include children older than one...
Oct 23, 2023
Second Dose of Palonosetron Reduces CINV in Pediatric Cancer Patients
An additional dose of palonosetron can help prevent chemotherapy-induced nausea and vomiting (CINV) in children with cancer who are...
Oct 19, 2023
FDA Approval of Bosulif Adds to Toolkit of Treatment Options for Children With CML
The Food and Drug Administration (FDA) has approved Bosulif (bosutinib) for the treatment of children as young as 1 year old with newly...
Oct 10, 2023
Breakthrough as new drug promises to shield child cancer patients from hearing loss
A new study, which is to be presented to the RNID Hearing Therapeutics Summit, found that a drug called Pedmark, also known as ...
Sep 13, 2023
New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors
For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain...
Aug 21, 2023