FDA Grants Rare Pediatric Designation to Elraglusib for Ewing Sarcoma
The FDA granted a rare pediatric disease designation to elraglusib (9-ING-41), a novel GSK-3β inhibitor, as a potential therapeutic...
Nov 18, 2024
Targeted therapy and radiation synergize in pediatric high-grade glioma
Research at St. Jude recently showed that the drug capmatinib is effective at crossing the blood-brain-barrier, synergizing with...
Nov 8, 2024
FDA Expands Approval for Jylamvo to Children With Acute Lymphoblastic Leukemia
The Food and Drug Administration (FDA) expanded the approval of Jylamvo (methotrexate) to include children with acute lymphoblastic...
Nov 5, 2024
New treatments offer hope for childhood cancer patients
Although the prognosis for most patients with pediatric cancer is good, one of the differences in treatment between childhood and adult...
Oct 15, 2024
Most cancer drugs must now be tested in paediatric cancers — unique PDX models can help
Approximately 75% of anticancer drugs must be tested against paediatric cancer. Drug developers can now use a database of patient-derived...
Sep 27, 2024
Breast cancer drug could help prolong survival for children with brain tumors, study finds
A drug called ribociclib, currently used to treat breast cancer , could slow the progression of certain pediatric high-grade gliomas, an...
Sep 20, 2024
Drug discovery could prevent spread of childhood bone cancer
Now, scientists at the University of British Columbia have identified a potential drug that could halt osteosarcoma's spread. In a study...
Sep 18, 2024
FDA Grants Orphan Drug Designation to Opaganib in Neuroblastoma
The FDA has granted a second orphan drug designation to opaganib in oncology, this time for patients with neuroblastoma. Read more:...
Sep 13, 2024
FDA Approves Retevmo for RET-Positive Pediatric Cancers
The Food and Drug Administration (FDA) granted an accelerated approval to Retevmo (selpercatinib) for the children aged two and older...
Jun 6, 2024
Development of novel therapies for pediatric cancer: Successes and challenges
Peter J. Houghton from Greehey Children’s Cancer Research Institute and Mary-Ann Bjornsti from the University of Alabama discuss some of...
Apr 3, 2024