FDA Approves Rare Pediatric Disease Designation for IMX-110 for Rhabdomyosarcoma
Officials with the FDA have approved a Rare Pediatric Disease Designation for IMX-110 for the treatment of pediatric patients with ...
Jan 19, 2022
FDA Approves Rylaze as Alternative for Patients with ALL and Lymphoblastic Lymphoma
New FDA approval means that pediatric and adult patients with acute lymphoblastic leukemia (ALL) and lympoblastic lymphoma who are...
Jul 2, 2021
Pediatric cancers have unique genetic vulnerabilities
Most cancer drugs that target specific genetic mutations are designed for adult cancers rather than those in children, partly because ...
Mar 26, 2021
PD-1 Blocker Safe in Childhood Cancers. But Does It Work?
PD-1-directed immunotherapy was safe and tolerable in children and adolescents with previously treated cancers, though responses were...
Mar 19, 2020
Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse
An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia...
Nov 5, 2019
The U.S. Is Running Out Of A Critical Childhood Cancer Drug And There Is No Suitable Replacement.
The U.S. is experiencing a critical shortage of a drug called vincristine, used to treat several types of childhood cancer including...
Oct 15, 2019
Which chemotherapy drugs have the highest cardiotoxicity risk in pediatric cancer?
A recent study published in JAMA Oncology analyzed data generated from over 28,000 childhood cancer survivors and compared the lifetime...
Apr 16, 2019
Drug Shortages Threaten Childhood Cancer Treatment
Despite the vital need for these drugs, they are often in short supply. A new paper published in JAMA Pediatrics discusses these drug...
Apr 2, 2019
Mitoxantrone for childhood cancer more cardiotoxic than thought
In pediatric cancer patients, mitoxantrone appears to be at least ten times as cardiotoxic as doxorubicin therapy, while daunorubicin...
Feb 14, 2019
Promising drug for pediatric leukemia in developing stages
Scientists from Northwestern Medicine have found that if they could stabilize the MLL protein -- the one responsible for the spread of...
Dec 28, 2018