Change in MYCN-driven cell state opens therapeutic window in high-risk neuroblastoma
A switch between cell states within MYCN-amplified neuroblastoma promotes KDM4, inhibition of which shows promising anticancer potential....
Apr 10, 2024
A team effort delivers a new tool for fighting neuroblastoma
Families of paediatric cancer patients have helped move a pioneering treatment for neuroblastoma from the lab to the clinic. Could this...
Mar 28, 2024
Study identifies patients who benefit most from dinutuximab-based immunotherapy
Using data from a randomized phase III clinical trial of neuroblastoma patients (treated with or without immunotherapy) performed by the...
Mar 26, 2024
Combining CAR-T cells and inhibitor drugs for high-risk neuroblastoma
Roberto Chiarle, MD, at Boston Children's Hospital and his colleagues now report a way to make CAR-T cell therapy work better in...
Mar 7, 2024
Universal, essential biomarker identified for childhood neuroblastoma
Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target...
Mar 5, 2024
New Resource for Selecting Best Treatment Path for Young Children with Cancerous Tumors Published by NCCN
New NCCN Guidelines for Neuroblastoma address the importance and impact of risk stratification for treating one of the more common types...
Feb 20, 2024
Cancer researcher 'beefing up' natural killer cells to stop cancer
A UCF cancer researcher is discovering ways that the body's own natural killer (NK) cells can be energized to fight deadly pediatric...
Feb 6, 2024
European scientists target high-risk childhood cancer with liquid biopsy
Liquid biopsies are a promise for the future of personalized cancer medicine: Many children with high-risk neuroblastoma, i.e. 50 percent...
Feb 2, 2024
New treatment improves outcomes for children with rare cancer
A new treatment for a rare form of children’s cancer – which combines anti-tumour drugs with chemotherapy – improves the chances of...
Jan 16, 2024
Researchers find Zika virus is effective when used to treat a type of childhood cancer in mice
Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could...
Jan 15, 2024

