Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor
- OPACC
- Apr 4, 2014
- 1 min read
The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in development of the bone cancer. The research was published today online ahead of print in the journal Cell Reports.
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