Distinct tumor 'neighborhoods' could guide more targeted treatments in aggressive childhood brain cancer
New research published in Nature finds that tumor cells within supratentorial ependymomas (SE)—an aggressive childhood brain cancer—cluster into distinct tumor cell populations. Read more: https://medicalxpress.com/news/2026-03-distinct-tumor-neighborhoods-treatments-aggressive.html
Mar 13
Hearing loss contributes to cognitive decline after childhood cancer treatment
Research from St. Jude led by Heather Conklin, PhD, Department of Psychology & Biobehavioral Sciences, demonstrated that radiation therapy was a significant individual contributor to hearing loss, a risk directly linked to cognitive health, in children treated for ependymoma. Read more: https://www.eurekalert.org/news-releases/1117443
Feb 25
Itaconate identified as a new target for pediatric brain tumors called ependymomas
In a study published in Nature , University of Michigan researchers have found that a specific molecule called itaconate drives the development of ependymomas. Their findings can help future drug development for children with this type of malignant brain tumor. Read more: https://www.michiganmedicine.org/health-lab/itaconate-identified-new-target-pediatric-brain-tumors-called-ependymomas
Feb 10
Serotonin-producing neurons regulate malignancy in ependymoma brain tumors
A collaborative study published in Nature reveals the functional relevance of tumor-neuron interactions that regulate the growth of...
Aug 9, 2024
New research out of Quebec gives hope for rare childhood cancer therapy
A joint university study has found that a pathway to a therapy program against a rare and deadly pediatric brain tumour is now possible....
Jul 10, 2024
Study Identifies Novel Epigenetic Changes in Pediatric Brain Cancer
Investigators have identified previously unknown sets of epigenetic changes in pediatric brain tumors, which could serve as novel ...
Dec 7, 2022
3D genomics reveals targets for aggressive childhood cancers
While some pediatric brain cancers have known genetic causes, many do not. Three-dimensional profiling revealed new disease mechanisms...
Nov 2, 2022
Common diabetes drug promising against rare childhood brain tumor in laboratory studies
Metformin, a drug commonly prescribed against diabetes, holds promise against a rare type of childhood brain tumor in laboratory...
Oct 12, 2021
Pediatric cancers share stalled gene-managing enzyme
A wildly out-of-place protein leads to haywire cells in a particularly troublesome type of rare early childhood cancer, according to...
Oct 21, 2020
A promising new treatment for recurrent pediatric brain cancer
Two pediatric brain cancers that are challenging to treat if they recur, medulloblastoma and ependymoma, are the target of a clinical...
Apr 30, 2020

