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Childhood Cancer Hijacks Cellular Quality Control System to Fuel Growth

A serious childhood cancer takes advantage of a quality control mechanism that usually protects cells from stress-induced damage to propel tumor growth, according to a new study led by researchers at UC San Francisco and the University of Pittsburgh. By blocking that mechanism, the scientists were able to kill cells derived from patients with rhabdomyosarcoma (RMS), a rare muscle-tissue cancer that affects a few hundred children in the U.S. each year.

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