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Researchers Discover Sugar-Addiction of Cancer Cells in Childhood Leukemia

An international team of researchers led by City of Hope’s Markus Müschen, M.D., Ph.D., the Norman and Sadie Lee Foundation Endowed Professor in Pediatrics and chair of the Department of Systems Biology, found a connection between drug-resistance in acute lymphoblastic leukemia (ALL) and increased sugar uptake in the ALL cells, according to the paper titled, “Metabolic gatekeeper function of B-lymphoid transcription factors,” published today in Nature.

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