In a study published in Cell Death & Disease, researchers led by Blanco identified a potential way to reduce relapse in medulloblastoma by targeting the tumor cells most likely to survive treatment and drive regrowth. Read more: https://www.news-medical.net/news/20260526/Scientists-target-root-of-relapse-in-aggressive-childhood-brain-tumors.aspx

Blocking energy production pathways in an aggressive type of brain cancer in children could be a promising new therapeutic strategy, according to research in mice by Johns Hopkins Kimmel Cancer Center investigators. Read more: https://www.hopkinsmedicine.org/news/newsroom/news-releases/2026/04/blocking-energy-metabolism-may-help-treat-aggressive-pediatric-brain-tumor

Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete understanding of how MYC expression is controlled in these tumors. Read more: https://www.eurekalert.org/news-releases/1125370

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Read more: https://www.technologynetworks.com/tn/news/three-childhood-cancers-have-a-shared-dependence-on-light-sensing-genes-410398

Survivors of childhood medulloblastoma who also had a history of posterior fossa syndrome experienced long-term neurocognitive and physical impairments, according to findings published in JAMA Network Open . Read more: https://www.cancertherapyadvisor.com/news/posterior-fossa-syndrome-neurocognitive-deficits-medulloblastoma-survivors/

Researchers at the University of Louisville used a modern statistical method to reanalyze the results of children with a special type of high-risk medulloblastoma called Group 3, who participated in two major national clinical trials of therapies. Read more: https://www.uoflnews.com/section/science-and-tech/unique-statistical-approach-lends-promise-to-therapies-for-rare-childhood-brain-cancer/

Higher levels of dihydrolipoyl transacetylase make Group-3 medulloblastomas vulnerable to copper-mediated death. Read more:...

Children who inherit a deficient ELP1 gene have an increased risk of developing SHH-medulloblastoma, a subtype of a malignant pediatric...

Researchers develop an explainable machine learning model to predict metastasis and survival in children with medulloblastoma. Read more:...

A team of researchers at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ) and Heidelberg...