Blocking energy production pathways in an aggressive type of brain cancer in children could be a promising new therapeutic strategy, according to research in mice by Johns Hopkins Kimmel Cancer Center investigators. Read more: https://www.hopkinsmedicine.org/news/newsroom/news-releases/2026/04/blocking-energy-metabolism-may-help-treat-aggressive-pediatric-brain-tumor

Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete understanding of how MYC expression is controlled in these tumors. Read more: https://www.eurekalert.org/news-releases/1125370

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Read more: https://www.technologynetworks.com/tn/news/three-childhood-cancers-have-a-shared-dependence-on-light-sensing-genes-410398

Survivors of childhood medulloblastoma who also had a history of posterior fossa syndrome experienced long-term neurocognitive and physical impairments, according to findings published in JAMA Network Open . Read more: https://www.cancertherapyadvisor.com/news/posterior-fossa-syndrome-neurocognitive-deficits-medulloblastoma-survivors/

Researchers at the University of Louisville used a modern statistical method to reanalyze the results of children with a special type of high-risk medulloblastoma called Group 3, who participated in two major national clinical trials of therapies. Read more: https://www.uoflnews.com/section/science-and-tech/unique-statistical-approach-lends-promise-to-therapies-for-rare-childhood-brain-cancer/

Higher levels of dihydrolipoyl transacetylase make Group-3 medulloblastomas vulnerable to copper-mediated death. Read more:...

Children who inherit a deficient ELP1 gene have an increased risk of developing SHH-medulloblastoma, a subtype of a malignant pediatric...

Researchers develop an explainable machine learning model to predict metastasis and survival in children with medulloblastoma. Read more:...

A team of researchers at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ) and Heidelberg...

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma—the most common type of...