Children and young adults with metastatic non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) continue to have “poor” survival outcomes despite the use of adaptive ifosfamide plus doxorubicin-based multimodal therapy, according to research published in the Journal of the National Cancer Institute. Read more: https://www.cancertherapyadvisor.com/news/outcomes-poor-children-non-rhabdomyosarcoma-soft-tissue-sarcoma/

A study has found that children continuously exposed to air pollutants generated during vehicle traffic, such as automobile exhaust, may face a higher risk of developing childhood cancers. Read more: https://www.chosun.com/english/national-en/2026/07/06/YPFTIRO4YNATBCAWYFJGJPFSC4/

Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy. The study, published in the journal Human Reproduction Open, may eventually contribute to new ways of protecting and restoring fertility after childhood cancer. Read more: https://medicalxpress.com/news/2026-07-testicular-tissue-early-germ-cells.html

A large European consortium will investigate environmental factors that may cause cancer in children, teenagers, and young adults. An increase in cancer diagnoses among adolescents and young adults suggests that environmental exposures may play a greater role than previously thought. Read more: https://www.prinsesmaximacentrum.nl/en/news/major-eu-study-to-investigate-the-role-of-environmental-factors-in-childhood-cancer

Researchers report encouraging early results from a first-in-human clinical trial led by Children's National Hospital using a new T-cell immunotherapy for children and young adults with some of the deadliest brain tumors, including diffuse intrinsic pontine glioma (DIPG) and relapsed central nervous system (CNS) tumors. Read more: https://medicalxpress.com/news/2026-06-tcell-therapy-tumor-proteins-early.html

Survivors of childhood cancer have a higher risk for antidepressant use and for combining these medications with other psychotropic drugs compared with individually-matched population references, according to findings published in EJC Paediatric Oncology. Read more: https://www.cancertherapyadvisor.com/news/childhood-cancer-survivors-antidepressants-other-psychotropics/

A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. The results, published in Molecular Therapy Oncology, present the first preclinical evidence showing the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer. Read more: https://medicalxpress.com/news/2026-06-anticancer-vaccine-early-success-neuroblastoma.html

Researchers at Wake Forest University School of Medicine found caregivers of children hospitalized for cancer and blood disorders may experience food insecurity during their child’s stay, even if they don’t face that issue at home, and it could be linked to longer stays. Read more: https://www.eurekalert.org/news-releases/1132410

Indiana University School of Medicine cancer researchers have identified a potential way to use existing, accessible drugs to combat juvenile myelomonocytic leukemia (JMML) by targeting a specific inflammatory pathway. Read more: https://firstwordpharma.com/story/7627533

In children and adolescents undergoing cancer treatment, exercise can be performed safely during and after therapy when appropriately supervised and individualized; further, appropriately prescribed exercise should be included as part of supportive cancer care, according to a new American College of Sports Medicine (ACSM) Expert Consensus Statement published by Fridh et al in the journal Medicine & Science in Sports & Exercise. Read more: https://ascopost.com/news/june-2026/n